How does bethanechol act on the bladder

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at Before taking bethanechol, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have:. This drug may make you dizzy. Alcohol or marijuana cannabis can make you more dizzy. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Limit alcoholic beverages.

Talk to your doctor if you are using marijuana cannabis. During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor. Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them.

Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first. Make sure laboratory personnel and all your doctors know you use this drug. This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use.

Keep a list of all your medications with you, and share the list with your doctor and pharmacist. If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call Otherwise, call a poison control center right away.

US residents can call their local poison control center at Canada residents can call a provincial poison control center. If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose.

Take your next dose at the regular time. Do not double the dose to catch up. Atropine; Benzoic Acid; Hyoscyamine; Methenamine; Methylene Blue; Phenyl Salicylate: Major The muscarinic actions of drugs known as parasympathomimetics, including both direct cholinergic receptor agonists and cholinesterase inhibitors, can antagonize the antimuscarinic actions of anticholinergic drugs, and vice versa.

Atropine; Difenoxin: Major The muscarinic actions of drugs known as parasympathomimetics, including both direct cholinergic receptor agonists and cholinesterase inhibitors, can antagonize the antimuscarinic actions of anticholinergic drugs, and vice versa.

Moderate Pharmacodynamic interactions between antidiarrheals and drugs that enhance peristalsis are theoretically possible. It is wise to avoid use of antidiarrheals in patients who require bethanechol. Atropine; Edrophonium: Major Cholinergic agonists can cause additive pharmacodynamic effects if used concomitantly with cholinesterase inhibitors.

Major The muscarinic actions of drugs known as parasympathomimetics, including both direct cholinergic receptor agonists and cholinesterase inhibitors, can antagonize the antimuscarinic actions of anticholinergic drugs, and vice versa.

Belladonna Alkaloids; Ergotamine; Phenobarbital: Major The muscarinic actions of drugs known as parasympathomimetics, including both direct cholinergic receptor agonists and cholinesterase inhibitors, can antagonize the antimuscarinic actions of anticholinergic drugs, and vice versa. Belladonna; Opium: Major The muscarinic actions of drugs known as parasympathomimetics, including both direct cholinergic receptor agonists and cholinesterase inhibitors, can antagonize the antimuscarinic actions of anticholinergic drugs, and vice versa.

Benzoic Acid; Hyoscyamine; Methenamine; Methylene Blue; Phenyl Salicylate: Major The muscarinic actions of drugs known as parasympathomimetics, including both direct cholinergic receptor agonists and cholinesterase inhibitors, can antagonize the antimuscarinic actions of anticholinergic drugs, and vice versa. Benzphetamine: Moderate Bethanechol offsets the effects of sympathomimetics at sites where sympathomimetic and cholinergic receptors have opposite effects.

Benztropine: Major The muscarinic actions of drugs known as parasympathomimetics, including both direct cholinergic receptor agonists and cholinesterase inhibitors, can antagonize the antimuscarinic actions of anticholinergic drugs, and vice versa. Bismuth Subsalicylate: Moderate Pharmacodynamic interactions between loperamide and drugs that enhance peristalsis are theoretically possible.

It is wise to avoid use loperamide in patients who require bethanechol. Bismuth Subsalicylate; Metronidazole; Tetracycline: Moderate Pharmacodynamic interactions between loperamide and drugs that enhance peristalsis are theoretically possible. Brompheniramine; Carbetapentane; Phenylephrine: Moderate Bethanechol offsets the effects of sympathomimetics at sites where sympathomimetic and cholinergic receptors have opposite effects.

Brompheniramine; Dextromethorphan; Phenylephrine: Moderate Bethanechol offsets the effects of sympathomimetics at sites where sympathomimetic and cholinergic receptors have opposite effects. Brompheniramine; Hydrocodone; Pseudoephedrine: Moderate Bethanechol offsets the effects of sympathomimetics at sites where sympathomimetic and cholinergic receptors have opposite effects. Brompheniramine; Phenylephrine: Moderate Bethanechol offsets the effects of sympathomimetics at sites where sympathomimetic and cholinergic receptors have opposite effects.

Brompheniramine; Pseudoephedrine: Moderate Bethanechol offsets the effects of sympathomimetics at sites where sympathomimetic and cholinergic receptors have opposite effects. Brompheniramine; Pseudoephedrine; Dextromethorphan: Moderate Bethanechol offsets the effects of sympathomimetics at sites where sympathomimetic and cholinergic receptors have opposite effects. Budesonide; Glycopyrrolate; Formoterol: Major The muscarinic actions of drugs known as parasympathomimetics, including both direct cholinergic receptor agonists and cholinesterase inhibitors, can antagonize the antimuscarinic actions of anticholinergic drugs, and vice versa.

Bupropion: Moderate Bupropion exhibits moderate anticholinergic properties. Avoid co-use when possible since the effects of bethanechol, a cholinergic agonist, may be diminished. If co-use is necessary, monitor for the intended clinical response. Bupropion; Naltrexone: Moderate Bupropion exhibits moderate anticholinergic properties. Carbetapentane; Chlorpheniramine; Phenylephrine: Moderate Bethanechol offsets the effects of sympathomimetics at sites where sympathomimetic and cholinergic receptors have opposite effects.

Carbetapentane; Diphenhydramine; Phenylephrine: Moderate Bethanechol offsets the effects of sympathomimetics at sites where sympathomimetic and cholinergic receptors have opposite effects. Moderate Drugs that possess antimuscarinic properties, such as diphenhydramine, are pharmacologic opposites of bethanechol.

Carbetapentane; Guaifenesin; Phenylephrine: Moderate Bethanechol offsets the effects of sympathomimetics at sites where sympathomimetic and cholinergic receptors have opposite effects. Carbetapentane; Phenylephrine: Moderate Bethanechol offsets the effects of sympathomimetics at sites where sympathomimetic and cholinergic receptors have opposite effects. Carbetapentane; Phenylephrine; Pyrilamine: Moderate Bethanechol offsets the effects of sympathomimetics at sites where sympathomimetic and cholinergic receptors have opposite effects.

Carbetapentane; Pseudoephedrine: Moderate Bethanechol offsets the effects of sympathomimetics at sites where sympathomimetic and cholinergic receptors have opposite effects. Carbinoxamine: Moderate Drugs that possess antimuscarinic properties, such as carbinoxamine, are pharmacologic opposites of bethanechol.

Carbinoxamine; Dextromethorphan; Pseudoephedrine: Moderate Bethanechol offsets the effects of sympathomimetics at sites where sympathomimetic and cholinergic receptors have opposite effects. Moderate Drugs that possess antimuscarinic properties, such as carbinoxamine, are pharmacologic opposites of bethanechol.

Carbinoxamine; Hydrocodone; Phenylephrine: Moderate Bethanechol offsets the effects of sympathomimetics at sites where sympathomimetic and cholinergic receptors have opposite effects. Carbinoxamine; Hydrocodone; Pseudoephedrine: Moderate Bethanechol offsets the effects of sympathomimetics at sites where sympathomimetic and cholinergic receptors have opposite effects.

Carbinoxamine; Phenylephrine: Moderate Bethanechol offsets the effects of sympathomimetics at sites where sympathomimetic and cholinergic receptors have opposite effects. Carbinoxamine; Pseudoephedrine: Moderate Bethanechol offsets the effects of sympathomimetics at sites where sympathomimetic and cholinergic receptors have opposite effects.

Cetirizine; Pseudoephedrine: Moderate Bethanechol offsets the effects of sympathomimetics at sites where sympathomimetic and cholinergic receptors have opposite effects. Cevimeline: Moderate Cevimeline and bethanechol are both cholinergic agonists. Coadministration is expected to result in additive parasympathomimetic effects. Chlophedianol; Dexchlorpheniramine; Pseudoephedrine: Moderate Bethanechol offsets the effects of sympathomimetics at sites where sympathomimetic and cholinergic receptors have opposite effects.

Chlophedianol; Guaifenesin; Phenylephrine: Moderate Bethanechol offsets the effects of sympathomimetics at sites where sympathomimetic and cholinergic receptors have opposite effects.

Chlordiazepoxide; Clidinium: Major The muscarinic actions of drugs known as parasympathomimetics, including both direct cholinergic receptor agonists and cholinesterase inhibitors, can antagonize the antimuscarinic actions of anticholinergic drugs, and vice versa. Chlorpheniramine; Dextromethorphan; Phenylephrine: Moderate Bethanechol offsets the effects of sympathomimetics at sites where sympathomimetic and cholinergic receptors have opposite effects.

Chlorpheniramine; Dextromethorphan; Pseudoephedrine: Moderate Bethanechol offsets the effects of sympathomimetics at sites where sympathomimetic and cholinergic receptors have opposite effects.

Chlorpheniramine; Dihydrocodeine; Phenylephrine: Moderate Bethanechol offsets the effects of sympathomimetics at sites where sympathomimetic and cholinergic receptors have opposite effects. Chlorpheniramine; Dihydrocodeine; Pseudoephedrine: Moderate Bethanechol offsets the effects of sympathomimetics at sites where sympathomimetic and cholinergic receptors have opposite effects. Chlorpheniramine; Guaifenesin; Hydrocodone; Pseudoephedrine: Moderate Bethanechol offsets the effects of sympathomimetics at sites where sympathomimetic and cholinergic receptors have opposite effects.

Chlorpheniramine; Hydrocodone; Phenylephrine: Moderate Bethanechol offsets the effects of sympathomimetics at sites where sympathomimetic and cholinergic receptors have opposite effects.

Chlorpheniramine; Hydrocodone; Pseudoephedrine: Moderate Bethanechol offsets the effects of sympathomimetics at sites where sympathomimetic and cholinergic receptors have opposite effects. Chlorpheniramine; Ibuprofen; Pseudoephedrine: Moderate Bethanechol offsets the effects of sympathomimetics at sites where sympathomimetic and cholinergic receptors have opposite effects.

Chlorpheniramine; Phenylephrine: Moderate Bethanechol offsets the effects of sympathomimetics at sites where sympathomimetic and cholinergic receptors have opposite effects.

Chlorpheniramine; Pseudoephedrine: Moderate Bethanechol offsets the effects of sympathomimetics at sites where sympathomimetic and cholinergic receptors have opposite effects. Chlorpromazine: Moderate Drugs that possess antimuscarinic properties, such as chlorpromazine, are pharmacologic opposites of bethanechol. Cholinesterase inhibitors: Major Cholinergic agonists can cause additive pharmacodynamic effects if used concomitantly with cholinesterase inhibitors.

Clemastine: Moderate Drugs that possess antimuscarinic properties, such as clemastine, are pharmacologic opposites of bethanechol. Clozapine: Moderate Drugs that possess antimuscarinic properties, such as clozapine, are pharmacologic opposites of bethanechol. Codeine; Guaifenesin; Pseudoephedrine: Moderate Bethanechol offsets the effects of sympathomimetics at sites where sympathomimetic and cholinergic receptors have opposite effects. Codeine; Phenylephrine; Promethazine: Moderate Bethanechol offsets the effects of sympathomimetics at sites where sympathomimetic and cholinergic receptors have opposite effects.

Moderate Drugs that possess antimuscarinic properties, such as promethazine, are pharmacologic opposites of bethanechol. Codeine; Promethazine: Moderate Drugs that possess antimuscarinic properties, such as promethazine, are pharmacologic opposites of bethanechol. Desloratadine; Pseudoephedrine: Moderate Bethanechol offsets the effects of sympathomimetics at sites where sympathomimetic and cholinergic receptors have opposite effects.

Dexbrompheniramine; Pseudoephedrine: Moderate Bethanechol offsets the effects of sympathomimetics at sites where sympathomimetic and cholinergic receptors have opposite effects.

Dexchlorpheniramine; Dextromethorphan; Pseudoephedrine: Moderate Bethanechol offsets the effects of sympathomimetics at sites where sympathomimetic and cholinergic receptors have opposite effects. Dexmethylphenidate: Moderate Bethanechol offsets the effects of sympathomimetics at sites where sympathomimetic and cholinergic receptors have opposite effects. Dextroamphetamine: Moderate Bethanechol offsets the effects of sympathomimetics at sites where sympathomimetic and cholinergic receptors have opposite effects.

Dextromethorphan; Diphenhydramine; Phenylephrine: Moderate Bethanechol offsets the effects of sympathomimetics at sites where sympathomimetic and cholinergic receptors have opposite effects.

Dextromethorphan; Guaifenesin; Phenylephrine: Moderate Bethanechol offsets the effects of sympathomimetics at sites where sympathomimetic and cholinergic receptors have opposite effects. Dextromethorphan; Guaifenesin; Pseudoephedrine: Moderate Bethanechol offsets the effects of sympathomimetics at sites where sympathomimetic and cholinergic receptors have opposite effects.

Dextromethorphan; Quinidine: Moderate Drugs that possess antimuscarinic properties, such as quinidine, are pharmacologic opposites of bethanechol. Dicyclomine: Major The muscarinic actions of drugs known as parasympathomimetics, including both direct cholinergic receptor agonists and cholinesterase inhibitors, can antagonize the antimuscarinic actions of anticholinergic drugs, and vice versa. Diethylpropion: Moderate Bethanechol offsets the effects of sympathomimetics at sites where sympathomimetic and cholinergic receptors have opposite effects.

Dihydrocodeine; Guaifenesin; Pseudoephedrine: Moderate Bethanechol offsets the effects of sympathomimetics at sites where sympathomimetic and cholinergic receptors have opposite effects.

Diphenhydramine: Moderate Drugs that possess antimuscarinic properties, such as diphenhydramine, are pharmacologic opposites of bethanechol. Diphenhydramine; Hydrocodone; Phenylephrine: Moderate Bethanechol offsets the effects of sympathomimetics at sites where sympathomimetic and cholinergic receptors have opposite effects. Diphenhydramine; Ibuprofen: Moderate Drugs that possess antimuscarinic properties, such as diphenhydramine, are pharmacologic opposites of bethanechol.

Diphenhydramine; Naproxen: Moderate Drugs that possess antimuscarinic properties, such as diphenhydramine, are pharmacologic opposites of bethanechol. Diphenhydramine; Phenylephrine: Moderate Bethanechol offsets the effects of sympathomimetics at sites where sympathomimetic and cholinergic receptors have opposite effects.

Diphenoxylate; Atropine: Major The muscarinic actions of drugs known as parasympathomimetics, including both direct cholinergic receptor agonists and cholinesterase inhibitors, can antagonize the antimuscarinic actions of anticholinergic drugs, and vice versa.

Disopyramide: Moderate Disopyramide possesses clinically significant antimuscarinic properties and these appear to be dose-related. It is possible that disopyramide could antagonize the muscarinic actions of cholinergic agonists. Clinicians should be alert to this possibility. Dobutamine: Moderate Bethanechol offsets the effects of sympathomimetics at sites where sympathomimetic and cholinergic receptors have opposite effects.

Donepezil: Major Cholinergic agonists can cause additive pharmacodynamic effects if used concomitantly with cholinesterase inhibitors. Donepezil; Memantine: Major Cholinergic agonists can cause additive pharmacodynamic effects if used concomitantly with cholinesterase inhibitors.

Dopamine: Moderate Bethanechol offsets the effects of sympathomimetics at sites where sympathomimetic and cholinergic receptors have opposite effects. Doxapram: Moderate Bethanechol offsets the effects of sympathomimetics at sites where sympathomimetic and cholinergic receptors have opposite effects.

Edrophonium: Major Cholinergic agonists can cause additive pharmacodynamic effects if used concomitantly with cholinesterase inhibitors. Ephedrine: Moderate Bethanechol offsets the effects of sympathomimetics at sites where sympathomimetic and cholinergic receptors have opposite effects. Ephedrine; Guaifenesin: Moderate Bethanechol offsets the effects of sympathomimetics at sites where sympathomimetic and cholinergic receptors have opposite effects.

Epinephrine: Moderate Bethanechol offsets the effects of sympathomimetics at sites where sympathomimetic and cholinergic receptors have opposite effects. Fexofenadine; Pseudoephedrine: Moderate Bethanechol offsets the effects of sympathomimetics at sites where sympathomimetic and cholinergic receptors have opposite effects. Flavoxate: Major The muscarinic actions of drugs known as parasympathomimetics, including both direct cholinergic receptor agonists and cholinesterase inhibitors, can antagonize the antimuscarinic actions of anticholinergic drugs, and vice versa.

Fosfomycin: Moderate Bethanechol increases gastrointestinal motility and may decrease the systemic absorption of fosfomycin when the drugs are coadministered. This may result in lower fosfomycin serum concentrations and urinary excretion. Inclusion Criteria: Women with cervical cancer stage IB - IIA underwent standard type III radical hysterectomy, both open and laparoscopic approach Patient aged 20 - 65 years Patient able to give free and informed consent and who agrees to participate be signing the consent form Exclusion Criteria: Patient who had an allergic reaction to bethanechol chloride Patient who had neurogenic bladder.

Contacts and Locations. Information from the National Library of Medicine To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor. Please refer to this study by its ClinicalTrials. More Information. National Library of Medicine U.

National Institutes of Health U. Department of Health and Human Services. The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Bladder Dysfunction. Drug: bethanechol chloride Device: early bladder training Other: early bladder training and bethanechol chloride Other: no early bladder training and no bethanechol chloride. Phase 4. Study Type :. Interventional Clinical Trial. Actual Enrollment :.

Actual Study Start Date :. Actual Primary Completion Date :. Actual Study Completion Date :. Experimental: A Ucholine Bethanechol chloride, 10 mg 2 tablets oral tid, ac Start on 3rd - 5th postoperative day In bethanechol chloride arm arm should be vital signs were monitored every 30 minute on first hour then every 4 hours on first day.

Drug: bethanechol chloride bethanechol chloride 10 2 tablets oral tid, ac. Experimental: B Early bladder training Start on 3rd - 5th postoperative day Remove urethral catheter on 5th postoperative day. Device: early bladder training early bladder training start on 3rd - 5thpostoperative day. Experimental: C Early bladder training and Ucholine Bethanechol chloride, 10 mg 2 tablets oral tid, ac Start on 3rd - 5th postoperative day should be vital signs were monitored every 30 minute on first hour then every 4 hours on first day.

Other: early bladder training and bethanechol chloride bethanechol chloride 2 tablets oral tid, ac and early bladder training start on 3rd - 5th postoperative day.